Causing a blow to the ruling alliance headed by the Pakistan Tehreek-i-Insaf (PTI) in the Senate elections from Islamabad, an upbeat opposition on Wednesday asked Prime Minister Imran Khan "to resign in an honourable way" after the defeat of the government's candidate Abdul Hafeez Shaikh at the hands of Pakistan Democra­tic Movement (PDM) candidate Syed Yousuf Raza Gilani. ....

In line with the previous government's China policy, the Biden administration has announced that the US will support China's neighbours, Taiwan and human rights in Hong Kong, Xinjiang and Tibet. ....

While describing the US engagement with India as a "global comprehensive strategic partnership," the State Department has reiterated Washington's policy of a de-hyphenated relationship with India and Pakistan saying it is "not a zero-sum." ....

Russia on Wednesday threatened to retaliate against the sanctions imposed on it by the US and the EU for allegedly poisoning an opposition leader. ....

Two patients at the long-term care hospitals in South Korea's Gyeonggi province died after receiving the AstraZeneca vaccine against Covid-19, the first cases of deaths since the country launched its nationwide vaccination programme last week. ....

The African countries of Guinea and the Democratic Republic of the Congo (DRC) have reported 28 Ebola virus cases and 11 deaths so far, the Africa Centers for Disease Control and Prevention said. ....

Mount Sinabung located on the Indonesian island of Sumatra erupted again on Tuesday, spewing ash clouds as high as 5,000 metres into the sky. ....

US President Joe Biden has appointed Indian-American Maju Varghese, who was the Chief Operating Officer of his campaign, as his deputy assistant and Director of the White House Military Office. ....

The UK's Prince Philip has been transferred to a different hospital for infection treatment and heart condition tests, a Buckingham Palace statement confirmed. ....

Prince William and his wife Duchess Catherine are encouraging people to take Covid-19 vaccination. The two also requested people to ignore misinformation being circulated about the vaccine. ....